Released on = August 8, 2007, 11:55 pm

Press Release Author = Premier Biosoft International

Industry = Biotech

Press Release Summary = PREMIER Biosoft International today announced the world wide
release of version 5 of AlleleID. AlleleID, which helps design microarrays and real
time PCR diagnostic assays for pathogen detection or bacterial identification will
now help MLPA® users design custom MLPA® probes.



Press Release Body = Palo Alto, California--April 15, 2007, PREMIER Biosoft
International today announced the world wide release of version 5 of AlleleID, the
only tool available for designing diagnostic assays for both real time PCR and
microarrays. AlleleID now includes support for designing custom probes for MLPA®
assays. AlleleID will help MLPA® users design custom oligos for genes that do not
have kits available.

Multiplex Ligation-dependent Probe Amplification (MLPA®) is a method to establish
the copy number of up to 45 nucleic acid sequences in a single reaction. MLPA®
probes are able to discriminate between sequences that differ by just one
nucleotide, making them a highly sensitive and precise tool for detecting the
changes. Current efforts are directed towards more comprehensive cataloging and
characterization of such changes.

For design support, the company has teamed up with MRC-Holland, the inventors of
MLPA® technology. \"With this collaboration, both PREMIER Biosoft and MRC-Holland
will use their core competencies and expertise to develop a powerful bioinformatics
tool for MLPA® users.\" commented Kay Brown, V.P. Business Development and Marketing.

AlleleID is a comprehensive desktop tool designed to address the challenges of
pathogen detection, bacterial identification or taxa/species discrimination using
microarrays and TaqMan® TaqMan® MGB, SYBR® Green and molecular beacon qPCR assays.
With ClustalW multiple sequence alignment at its core, AlleleID can design species
specific/cross species probes for microarrays or TaqMan®, TaqMan® MGB, SYBR® Green
and molecular beacon qPCR assays.

AlleleID employs a sophisticated algorithm to assure assay success. Highly specific
oligos are designed by avoiding regions of significant homology found by
automatically interpreting BLAST search results. The oligos designed can be BLAST
searched, to verify their specificity. Primer efficiency is enhanced by
automatically avoiding template secondary structures.

For details, please visit:
http://www.premierbiosoft.com/bacterial-identification/index.html


About PREMIER Biosoft International:
Founded in 1994, the company is a group of computer scientists and molecular
biologists dedicated to producing cutting edge intuitive software for the molecular
biologist. The goal of the company is to study the most recent innovations in
molecular biology and translate them into software products that aid biologists.
Additional information about PREMIER Biosoft International can be found at
http://www.PremierBiosoft.com

Contact:
Arun Apte
PREMIER Biosoft International
650-856-2703
http://www.PremierBiosoft.com

Web Site = http://www.premierbiosoft.com

Contact Details = 3786, Corina Way,
Palo Alto
650-856-2703
Fax: 650-618-1773
support2premierbiosoft.com