Released on: October 16, 2008, 2:48 pm

Press Release Author: AnaSpec Inc.

Industry: Biotech

Press Release Summary: MMPs are key players in normal and pathological processes,
including embryogenesis, wound healing, inflammation, arthritis, and cancer.

Press Release Body: San Jose, CA - October 16, 2008

Matrix metalloproteinases (MMPs) belong to a family of secreted or
membrane-associated zinc endopeptidases involved in both normal and diseased tissue
remodeling. They are capable of degrading all kinds of extracellular matrix (ECM)
proteins, but also can process a number of bioactive molecules. MMPs are key players
in normal and pathological processes, including embryogenesis, wound healing,
inflammation, arthritis, and cancer.

MMPs share common structural and functional elements and are products of different
genes. The three common domains include the pro-peptide, the catalytic domain and
the haemopexin-like C-terminal domain linked to the catalytic domain by a flexible
hinge region. MMPs are initially synthesized as inactive (latent) zymogens with a
pro-peptide domain that must be removed before the enzyme is active.

AnaSpec is pleased to complement its MMP product line with a suite of SensoLyteTM
MMP ELISA Kits. These kits are ideal for quantitative detection of MMP proteins
(latent and active forms) in serum, plasma, cell culture supernates and urine. The
SensoLyteTM ELISA Kits use a convenient, 96-well plate based format with
colorimetric read-out.

AnaSpec's widely used fluorescent SensoLyteTM MMP Activity Assays measure active
MMPs in a convenient, 96-well plate-based method with highly sensitive fluorimetric
read-out. A colorimetric read-out MMP Activity Assay kit is also available.

About AnaSpec

AnaSpec is a leading provider of integrated proteomics solutions to the world's
largest biotech, pharmaceutical, and academic research institutions. With a vision
for innovation through synergy, AnaSpec focuses on three core technologies:
peptides, detection reagents, and combinatorial chemistry.

For more information visit www.anaspec.com

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Web Site: http://www.anaspec.com

Contact Details: AnaSpec Inc.
2149 O'Toole Ave.
San Jose, CA 95131
1-408-452-5055 (Tel)
1-408-452-5059 (Fax)
1-800-452-5530
ping@anaspec.com
www.anaspec.com